Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
7R01AR035166-04
Application #
3157072
Study Section
Oral Biology and Medicine Study Section (OBM)
Project Start
1989-02-01
Project End
1989-12-31
Budget Start
1989-02-01
Budget End
1989-12-31
Support Year
4
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Lian, J B; Stein, G S (1995) Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation. Iowa Orthop J 15:118-40
Heinrichs, A A; Bortell, R; Bourke, M et al. (1995) Proximal promoter binding protein contributes to developmental, tissue-restricted expression of the rat osteocalcin gene. J Cell Biochem 57:90-100
Lynch, M P; Stein, J L; Stein, G S et al. (1995) The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralizatio Exp Cell Res 216:35-45
Shalhoub, V; Bettencourt, B; Jackson, M E et al. (1994) Abnormalities of phosphoprotein gene expression in three osteopetrotic rat mutations: elevated mRNA transcripts, protein synthesis, and accumulation in bone of mutant animals. J Cell Physiol 158:110-20
Breen, E C; Ignotz, R A; McCabe, L et al. (1994) TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype. J Cell Physiol 160:323-35
Bidwell, J P; van Wijnen, A J; Fey, E G et al. (1994) Subnuclear distribution of the vitamin D receptor. J Cell Biochem 54:494-500
Bidwell, J; van Wijnen, A; Banerjee, C et al. (1994) Parathyroid-responsive modifications in the nuclear matrix of ROS 17/2.8 rat osteosarcoma cells. Endocrinology 134:1738-44
Stein, G S; van Wijnen, A J; Stein, J L et al. (1994) Nuclear architecture supports integration of physiological regulatory signals for transcription of cell growth and tissue-specific genes during osteoblast differentiation. J Cell Biochem 55:4-15
Bidwell, J P; Fey, E G; van Wijnen, A J et al. (1994) Nuclear matrix proteins distinguish normal diploid osteoblasts from osteosarcoma cells. Cancer Res 54:28-32
Stein, G S; Stein, J L; van Wijnen, A J et al. (1994) Histone gene transcription: a model for responsiveness to an integrated series of regulatory signals mediating cell cycle control and proliferation/differentiation interrelationships. J Cell Biochem 54:393-404

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