Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
3R01AR038170-04S1
Application #
3158444
Study Section
General Medicine B Study Section (GMB)
Project Start
1986-04-01
Project End
1991-03-31
Budget Start
1989-08-01
Budget End
1990-03-31
Support Year
4
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
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Ozono, K; Sone, T; Pike, J W (1991) The genomic mechanism of action of 1,25-dihydroxyvitamin D3. J Bone Miner Res 6:1021-7
Ozono, K; Liao, J; Kerner, S A et al. (1990) The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer. J Biol Chem 265:21881-8
Liao, J; Ozono, K; Sone, T et al. (1990) Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A 87:9751-5
McDonnell, D P; Scott, R A; Kerner, S A et al. (1989) Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. Mol Endocrinol 3:635-44
Kerner, S A; Scott, R A; Pike, J W (1989) Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3. Proc Natl Acad Sci U S A 86:4455-9
Clemens, T L; Garrett, K P; Zhou, X Y et al. (1988) Immunocytochemical localization of the 1,25-dihydroxyvitamin D3 receptor in target cells. Endocrinology 122:1224-30
Allegretto, E A; Pike, J W; Haussler, M R (1987) Immunochemical detection of unique proteolytic fragments of the chick 1,25-dihydroxyvitamin D3 receptor. Distinct 20-kDa DNA-binding and 45-kDa hormone-binding species. J Biol Chem 262:1312-9
Allegretto, E A; Pike, J W; Haussler, M R (1987) C-terminal proteolysis of the avian 1,25-dihydroxyvitamin D3 receptor. Biochem Biophys Res Commun 147:479-85
Pike, J W; Sleator, N M; Haussler, M R (1987) Chicken intestinal receptor for 1,25-dihydroxyvitamin D3. Immunologic characterization and homogeneous isolation of a 60,000-dalton protein. J Biol Chem 262:1305-11