Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR039577-02
Application #
3159724
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1989-02-01
Project End
1992-01-31
Budget Start
1990-02-01
Budget End
1991-01-31
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Oklahoma Medical Research Foundation
Department
Type
DUNS #
937727907
City
Oklahoma City
State
OK
Country
United States
Zip Code
73104
James, J A; McClain, M T; Koelsch, G et al. (1999) Side-chain specificities and molecular modelling of peptide determinants for two anti-Sm B/B' autoantibodies. J Autoimmun 12:43-9
Huang, S C; Scofield, R H; Kurien, B T et al. (1997) Human anti-Ro autoantibodies bind multiple conformational epitopes of 60-kD Ro autoantigen. J Clin Immunol 17:212-9
Scofield, R H; Dickey, W D; Hardgrave, K L et al. (1995) Immunogenetics of epitopes of the carboxyl terminus of the human 60-kD Ro autoantigen. Clin Exp Immunol 99:256-61
James, J A; Harley, J B (1995) Peptide autoantigenicity of the small nuclear ribonucleoprotein C. Clin Exp Rheumatol 13:299-305
James, J A; Gross, T; Scofield, R H et al. (1995) Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity. J Exp Med 181:453-61
James, J A; Scofield, R H; Harley, J B (1994) Basic amino acids predominate in the sequential autoantigenic determinants of the small nuclear 70K ribonucleoprotein. Scand J Immunol 39:557-66
Alexander, E L; Ranzenbach, M R; Kumar, A J et al. (1994) Anti-Ro(SS-A) autoantibodies in central nervous system disease associated with Sjogren's syndrome (CNS-SS): clinical, neuroimaging, and angiographic correlates. Neurology 44:899-908
Dickey, W D; Harley, J B; Scofield, R H (1994) Human autoantibody production in the severe combined immunodeficiency (scid) mouse. Clin Exp Rheumatol 12:157-61
Hardgrave, K L; Neas, B R; Scofield, R H et al. (1993) Antibodies to vesicular stomatitis virus proteins in patients with systemic lupus erythematosus and in normal subjects. Arthritis Rheum 36:962-70
Williams Jr, R C; Malone, C C; Harley, J B (1993) Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human beta 2-microglobulin. Arthritis Rheum 36:916-26

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