Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR039754-01
Application #
3159980
Study Section
Biophysics and Biophysical Chemistry A Study Section (BBCA)
Project Start
1988-12-01
Project End
1991-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Mahaney, J E; Froehlich, J P; Thomas, D D (1995) Conformational transitions of the sarcoplasmic reticulum Ca-ATPase studied by time-resolved EPR and quenched-flow kinetics. Biochemistry 34:4864-79
Berger, C L; Thomas, D D (1993) Rotational dynamics of actin-bound myosin heads in active myofibrils. Biochemistry 32:3812-21
Ostap, E M; White, H D; Thomas, D D (1993) Transient detection of spin-labeled myosin subfragment 1 conformational states during ATP hydrolysis. Biochemistry 32:6712-20
Tanner, J W; Thomas, D D; Goldman, Y E (1992) Transients in orientation of a fluorescent cross-bridge probe following photolysis of caged nucleotides in skeletal muscle fibres. J Mol Biol 223:185-203
Lewis, S M; Thomas, D D (1992) Resolved conformational states of spin-labeled Ca-ATPase during the enzymatic cycle. Biochemistry 31:7381-9
Lewis, S M; Thomas, D D (1991) Microsecond rotational dynamics of spin-labeled Ca-ATPase during enzymatic cycling initiated by photolysis of caged ATP. Biochemistry 30:8331-9
Ostap, E M; Thomas, D D (1991) Rotational dynamics of spin-labeled F-actin during activation of myosin S1 ATPase using caged ATP. Biophys J 59:1235-41
Fajer, P G; Fajer, E A; Matta, J J et al. (1990) Effect of ADP on the orientation of spin-labeled myosin heads in muscle fibers: a high-resolution study with deuterated spin labels. Biochemistry 29:5865-71
Fajer, P G; Fajer, E A; Thomas, D D (1990) Myosin heads have a broad orientational distribution during isometric muscle contraction: time-resolved EPR studies using caged ATP. Proc Natl Acad Sci U S A 87:5538-42
Stein, R A; Ludescher, R D; Dahlberg, P S et al. (1990) Time-resolved rotational dynamics of phosphorescent-labeled myosin heads in contracting muscle fibers. Biochemistry 29:10023-31

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