Glucocorticoid Regulation of Procollagen Gene Expression

Cutroneo, Kenneth R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Research Project (R01)
• Project #: 5R01AR040154-03
• Application #: 2079868
• Study Section: Pathobiochemistry Study Section (PBC)
• Project Start: 1994-03-10
• Project End: 1998-02-28
• Budget Start: 1996-03-01
• Budget End: 1997-02-28
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Vermont & St Agric College
• Department: Biochemistry
• Type: Schools of Medicine
• DUNS #: 066811191
• City: Burlington
• State: VT
• Country: United States
• Zip Code: 05405

Publications

Parrelli, J M; Meisler, N; Cutroneo, K R (1998) Identification of a glucocorticoid response element in the human transforming growth factor beta 1 gene promoter. Int J Biochem Cell Biol 30:623-7

Meisler, N T; Parrelli, J; Gendimenico, G J et al. (1997) All-trans-retinoic acid inhibition of Pro alpha1(I) collagen gene expression in fetal rat skin fibroblasts: identification of a retinoic acid response element in the Pro alpha1(I) collagen gene. J Invest Dermatol 108:476-81

Meisler, N; Keefer, K A; Ehrlich, H P et al. (1997) Dexamethasone abrogates the fibrogenic effect of transforming growth factor-beta in rat granuloma and granulation tissue fibroblasts. J Invest Dermatol 108:285-9

Shull, S; Meisler, N; Absher, M et al. (1995) Glucocorticoid-induced down regulation of transforming growth factor-beta 1 in adult rat lung fibroblasts. Lung 173:71-8

Meisler, N; Shull, S; Xie, R et al. (1995) Glucocorticoids coordinately regulate type I collagen pro alpha 1 promoter activity through both the glucocorticoid and transforming growth factor beta response elements: a novel mechanism of glucocorticoid regulation of eukaryotic genes. J Cell Biochem 59:376-88