Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR041006-03
Application #
2080402
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1993-08-12
Project End
1997-06-30
Budget Start
1995-08-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Southern California
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Stohl, William; Xu, Dong; Kim, Kyoung Soo et al. (2004) MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4). Int Immunol 16:895-904
Stohl, W; Metyas, S; Tan, S-M et al. (2004) Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus. Ann Rheum Dis 63:1096-103
Stohl, William; Metyas, Samy; Tan, Soon-Min et al. (2003) B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. Arthritis Rheum 48:3475-86
Tan, Soon-Min; Xu, Dong; Roschke, Viktor et al. (2003) Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum 48:982-92
Kim, Kyoung Soo; Jacob, Noam; Stohl, William (2003) In vitro and in vivo T cell oligoclonality following chronic stimulation with staphylococcal superantigens. Clin Immunol 108:182-9
Stohl, William; Cheema, Gurtej S; Briggs, William S et al. (2002) B lymphocyte stimulator protein-associated increase in circulating autoantibody levels may require CD4+ T cells: lessons from HIV-infected patients. Clin Immunol 104:115-22
Stohl, William (2002) B lymphocyte stimulator protein levels in systemic lupus erythematosus and other diseases. Curr Rheumatol Rep 4:345-50
Roschke, Viktor; Sosnovtseva, Svetlana; Ward, Christopher D et al. (2002) BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol 169:4314-21
Stohl, William (2002) Systemic lupus erythematosus: a blissless disease of too much BLyS (B lymphocyte stimulator) protein. Curr Opin Rheumatol 14:522-8
Parr, T B; Hofman, F M; Kiener, P A et al. (2001) Cell cycle phase-specific survival of CD95 ligand-challenged Jurkat cells: upregulation of heat-shock response. Cell Immunol 211:21-9

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