Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR042359-03
Application #
2081549
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1993-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of South Carolina at Columbia
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
111310249
City
Columbia
State
SC
Country
United States
Zip Code
29208

  Publications

Wu, Licia N Y; Genge, Brian R; Wuthier, Roy E (2008) Analysis and molecular modeling of the formation, structure, and activity of the phosphatidylserine-calcium-phosphate complex associated with biomineralization. J Biol Chem 283:3827-38
Genge, Brian R; Wu, Licia N Y; Wuthier, Roy E (2008) Mineralization of annexin-5-containing lipid-calcium-phosphate complexes: modulation by varying lipid composition and incubation with cartilage collagens. J Biol Chem 283:9737-48
Genge, Brian R; Wu, Licia N Y; Wuthier, Roy E (2007) In vitro modeling of matrix vesicle nucleation: synergistic stimulation of mineral formation by annexin A5 and phosphatidylserine. J Biol Chem 282:26035-45
Wu, L N Y; Genge, B R; Ishikawa, Y et al. (2006) Effects of 24R,25- and 1alpha,25-dihydroxyvitamin D3 on mineralizing growth plate chondrocytes. J Cell Biochem 98:309-34
Wu, Licia N Y; Ishikawa, Yoshinori; Genge, Brian R et al. (2005) Chondrocytes isolated from tibial dyschondroplasia lesions and articular cartilage revert to a growth plate-like phenotype when cultured in vitro. J Cell Physiol 202:167-77
Nie, D; Ishikawa, Y; Yoshimori, T et al. (1998) Retinoic acid treatment elevates matrix metalloproteinase-2 protein and mRNA levels in avian growth plate chondrocyte cultures. J Cell Biochem 68:90-9
Ishikawa, Y; Genge, B R; Wuthier, R E et al. (1998) Thyroid hormone inhibits growth and stimulates terminal differentiation of epiphyseal growth plate chondrocytes. J Bone Miner Res 13:1398-411
Sauer, G R; Nie, D; Wu, L N et al. (1998) Induction and characterization of metallothionein in chicken epiphyseal growth plate cartilage chondrocytes. J Cell Biochem 68:110-20
Nie, D; Ishikawa, Y; Guo, Y et al. (1998) Inhibition of terminal differentiation and matrix calcification in cultured avian growth plate chondrocytes by Rous sarcoma virus transformation. J Cell Biochem 69:453-62
Wu, L N; Wuthier, M G; Genge, B R et al. (1997) In situ levels of intracellular Ca2+ and pH in avian growth plate cartilage. Clin Orthop Relat Res :310-24

Showing the most recent 10 out of 14 publications