Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR042489-03
Application #
2081788
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1993-12-10
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Vermont & St Agric College
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Wilson, D J; Alessandrini, A; Budd, R C (1999) MEK1 activation rescues Jurkat T cells from Fas-induced apoptosis. Cell Immunol 194:67-77
Fortner, K A; Russell, J Q; Budd, R C (1998) Down-modulation of CD2 delays deletion of superantigen-responsive T cells. Eur J Immunol 28:70-9
Kennedy, N J; Budd, R C (1998) Phosphorylation of FADD/MORT1 and Fas by kinases that associate with the membrane-proximal cytoplasmic domain of Fas. J Immunol 160:4881-8
Wilson, D J; Fortner, K A; Lynch, D H et al. (1996) JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells. Eur J Immunol 26:989-94
Mixter, P F; Russell, J Q; Durie, F H et al. (1995) Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin. J Immunol 154:2063-74
Budd, R C; Mixter, P F (1995) The origin of CD4-CD8-TCR alpha beta+ thymocytes: a model based on T-cell receptor avidity. Immunol Today 16:428-31
Clements, J L; Cooper, S M; Budd, R C (1995) Abnormal regulation of the IL-2 promoter in lpr CD4-CD8- T lymphocytes results in constitutive expression of a novel nuclear factor of activated T cells-binding factor. J Immunol 154:6372-81
Mixter, P F; Russell, J Q; Budd, R C (1994) Delayed kinetics of T lymphocyte anergy and deletion in lpr mice. J Autoimmun 7:697-710