Tgf Beta Signaling in Cartilage Repair

Benya, Paul David

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Research Project (R01)
• Project #: 5R01AR042894-03
• Application #: 2082422
• Study Section: Orthopedics and Musculoskeletal Study Section (ORTH)
• Project Start: 1994-07-29
• Project End: 1998-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Southern California
• Department: Orthopedics
• Type: Schools of Medicine
• DUNS #: 041544081
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90089

Publications

Qiao, Bo; Padilla, Silvia R; Benya, Paul D (2005) Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling. J Biol Chem 280:17562-71

Lowe, G N; Fu, Y H; McDougall, S et al. (1996) Effects of prostaglandins on deoxyribonucleic acid and aggrecan synthesis in the RCJ 3.1C5.18 chondrocyte cell line: role of second messengers. Endocrinology 137:2208-16

McDougall, S; Fu, Y H; Lowe, G N et al. (1996) Surface adhesion-mediated regulation of chondrocyte-specific gene expression in the nontransformed RCJ 3.1C5.18 rat chondrocyte cell line. J Bone Miner Res 11:1130-8