Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR043384-01A2
Application #
2006445
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1996-09-30
Project End
2000-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rush University Medical Center
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612
Knudson, Warren; Ishizuka, Shinya; Terabe, Kenya et al. (2018) The pericellular hyaluronan of articular chondrocytes. Matrix Biol :
Danielson, Ben T; Knudson, Cheryl B; Knudson, Warren (2015) Extracellular processing of the cartilage proteoglycan aggregate and its effect on CD44-mediated internalization of hyaluronan. J Biol Chem 290:9555-70
Hida, Daisuke; Danielson, Ben T; Knudson, Cheryl B et al. (2015) CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2. Matrix Biol 48:42-54
Luo, Na; Knudson, Warren; Askew, Emily B et al. (2014) CD44 and hyaluronan promote the bone morphogenetic protein 7 signaling response in murine chondrocytes. Arthritis Rheumatol 66:1547-58
Ariyoshi, W; Okinaga, T; Knudson, C B et al. (2014) High molecular weight hyaluronic acid regulates osteoclast formation by inhibiting receptor activator of NF-*B ligand through Rho kinase. Osteoarthritis Cartilage 22:111-20
Ono, Yohei; Sakai, Tadahiro; Hiraiwa, Hideki et al. (2013) Chondrogenic capacity and alterations in hyaluronan synthesis of cultured human osteoarthritic chondrocytes. Biochem Biophys Res Commun 435:733-9
Mellor, Liliana; Knudson, Cheryl B; Hida, Daisuke et al. (2013) Intracellular domain fragment of CD44 alters CD44 function in chondrocytes. J Biol Chem 288:25838-50
Ariyoshi, Wataru; Takahashi, Nobunori; Hida, Daisuke et al. (2012) Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides. Arthritis Rheum 64:187-97
Patchigolla, R Krishna R; Knudson, Warren; Schmid, Thomas M (2012) Matrix metalloproteinase-9 in a unique proteoglycan form in avian embryonic growth plate cartilage. Arch Biochem Biophys 520:42-50
Takahashi, Nobunori; Knudson, Cheryl B; Thankamony, Sai et al. (2010) Induction of CD44 cleavage in articular chondrocytes. Arthritis Rheum 62:1338-48

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