Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR043518-02
Application #
2083220
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1995-05-06
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Waterman, Wayne R; Xu, Li Lian; Tetradis, Sotirios et al. (2006) Glucocorticoid inhibits the human pro-interleukin lbeta gene (ILIB) by decreasing DNA binding of transactivators to the signal-responsive enhancer. Mol Immunol 43:773-82
Lian, Jian P; Crossley, Lisa; Zhan, Qian et al. (2002) The P21-activated protein kinases (Paks) receive and integrate messages from a variety of signaling pathways. Adv Exp Med Biol 507:497-502
Robinson, D; Huang, R; Lian, J P et al. (1999) Functions of the p21-activated protein kinases (Paks) in neutrophils and their regulation by complex lipids. Adv Exp Med Biol 469:385-90
Lian, J P; Huang, R; Robinson, D et al. (1999) Activation of p90RSK and cAMP response element binding protein in stimulated neutrophils: novel effects of the pyridinyl imidazole SB 203580 on activation of the extracellular signal-regulated kinase cascade. J Immunol 163:4527-36
Lian, J P; Huang, R; Robinson, D et al. (1998) Products of sphingolipid catabolism block activation of the p21-activated protein kinases in neutrophils. J Immunol 161:4375-81
Huang, R; Lian, J P; Robinson, D et al. (1998) Neutrophils stimulated with a variety of chemoattractants exhibit rapid activation of p21-activated kinases (Paks): separate signals are required for activation and inactivation of paks. Mol Cell Biol 18:7130-8
Sperling, R I (1998) The effects of dietary n-3 polyunsaturated fatty acids on neutrophils. Proc Nutr Soc 57:527-34
Robinson, D R; Urakaze, M; Huang, R et al. (1996) Dietary marine lipids suppress continuous expression of interleukin-1 beta gene transcription. Lipids 31 Suppl:S23-31