A simple model is proposed to explain how the central nervous system (CNS) coordinates the muscles at two or more joints of a single limb, when making a voluntary pointing movement. This model has three elements: a general principle for inter-joint torque coordination, and two movement-specific rules. One rule determines the signs and magnitudes of the individual joint torques, while a second specifies the joint torque patterns. From these torques, the muscles which act as agonists and antagonists can be identified, and their patterns of activation can be approximately specified. The model also identifies regions where this agonist/antagonist pattern breaks down.
The aim of the proposed study is to test the validity of this model, in the context of two-joint arm pointing movements, and to test the limits of the model's generalizability by applying it to other limbs, to more joints, and to other classes of movements. It is suggested by the applicant that this model offers a concrete, physically meaningful approach to what """"""""coordination"""""""" is and how a lack of coordination might be measured.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR044388-04
Application #
6171476
Study Section
Special Emphasis Panel (ZRG4-ORTH (03))
Program Officer
Panagis, James S
Project Start
1997-06-01
Project End
2002-05-31
Budget Start
2000-06-01
Budget End
2002-05-31
Support Year
4
Fiscal Year
2000
Total Cost
$172,961
Indirect Cost
Name
Boston University
Department
Type
Organized Research Units
DUNS #
042250712
City
Boston
State
MA
Country
United States
Zip Code
02215
Shemmell, Jonathan; Corcos, Daniel M; Hasan, Ziaul (2009) Kinetic and kinematic adaptation to anisotropic load. Exp Brain Res 192:1-8
Lee, Dongpyo; Corcos, Daniel M; Shemmell, Jonathan et al. (2008) Resolving kinematic redundancy in target-reaching movements with and without external constraint. Exp Brain Res 191:67-81
Shapiro, Mark B; Prodoehl, Janey; Corcos, Daniel M et al. (2005) Muscle activation is different when the same muscle acts as an agonist or an antagonist during voluntary movement. J Mot Behav 37:135-45
Shapiro, Mark B; Gottlieb, Gerald L; Corcos, Daniel M (2004) EMG responses to an unexpected load in fast movements are delayed with an increase in the expected movement time. J Neurophysiol 91:2135-47
Gottlieb, G L (2001) Influence of strategy on muscle activity during impact movements. J Mot Behav 33:235-42
Zaal, F T; Daigle, K; Gottlieb, G L et al. (1999) An unlearned principle for controlling natural movements. J Neurophysiol 82:255-9
Gottlieb, G L (1998) Muscle activation patterns during two types of voluntary single-joint movement. J Neurophysiol 80:1860-7