Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR044894-07
Application #
6690000
Study Section
Immunological Sciences Study Section (IMS)
Program Officer
Gretz, Elizabeth
Project Start
1998-01-15
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
7
Fiscal Year
2004
Total Cost
$378,300
Indirect Cost

  Institution

Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390

  Publications

Wu, Tianfu; Ye, Yujin; Min, So-Youn et al. (2014) Prevention of murine lupus nephritis by targeting multiple signaling axes and oxidative stress using a synthetic triterpenoid. Arthritis Rheumatol 66:3129-39
Liang, Zhiyan; Chang, Sooghee; Youn, Min So et al. (2009) Molecular hallmarks of anti-chromatin antibodies associated with the lupus susceptibility locus, Sle1. Mol Immunol 46:2671-81
Xie, Chun; Patel, Rahul; Wu, Tianfu et al. (2007) PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr. Int Immunol 19:509-22
Wu, Tianfu; Qin, Xiangmei; Kurepa, Zoran et al. (2007) Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus. J Clin Invest 117:2186-96
Kumar, Kirthi Raman; Li, Liunan; Yan, Mei et al. (2006) Regulation of B cell tolerance by the lupus susceptibility gene Ly108. Science 312:1665-9
Wakui, Masatoshi; Morel, Laurence; Butfiloski, Edward J et al. (2005) Genetic dissection of systemic lupus erythematosus pathogenesis: partial functional complementation between Sle1 and Sle3/5 demonstrates requirement for intracellular coexpression for full phenotypic expression of lupus. J Immunol 175:1337-45
Sobel, Eric S; Morel, Laurence; Baert, Raquel et al. (2002) Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells. J Immunol 169:4025-32
Mohan, C; Yu, Y; Morel, L et al. (1999) Genetic dissection of Sle pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death. J Immunol 162:6492-502