Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR047839-02
Application #
6689565
Study Section
Special Emphasis Panel (ZRG1-SSS-M (01))
Program Officer
Panagis, James S
Project Start
2002-12-10
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$273,111
Indirect Cost
Name
Rice University
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
050299031
City
Houston
State
TX
Country
United States
Zip Code
77005
Huang, Brian J; Huey, Daniel J; Hu, Jerry C et al. (2017) Engineering biomechanically functional neocartilage derived from expanded articular chondrocytes through the manipulation of cell-seeding density and dexamethasone concentration. J Tissue Eng Regen Med 11:2323-2332
Makris, Eleftherios A; Huang, Brian J; Hu, Jerry C et al. (2015) Digoxin and adenosine triphosphate enhance the functional properties of tissue-engineered cartilage. Tissue Eng Part A 21:884-94
Hadidi, Pasha; Yeh, Timothy C; Hu, Jerry C et al. (2015) Critical seeding density improves the properties and translatability of self-assembling anatomically shaped knee menisci. Acta Biomater 11:173-82
Lee, Jennifer K; Responte, Donald J; Cissell, Derek D et al. (2014) Clinical translation of stem cells: insight for cartilage therapies. Crit Rev Biotechnol 34:89-100
Higashioka, Michael M; Chen, Justin A; Hu, Jerry C et al. (2014) Building an anisotropic meniscus with zonal variations. Tissue Eng Part A 20:294-302
Huey, Daniel J; Hu, Jerry C; Athanasiou, Kyriacos A (2013) Chondrogenically tuned expansion enhances the cartilaginous matrix-forming capabilities of primary, adult, leporine chondrocytes. Cell Transplant 22:331-40
Huey, Daniel J; Athanasiou, Kyriacos A (2013) Alteration of the fibrocartilaginous nature of scaffoldless constructs formed from leporine meniscus cells and chondrocytes through manipulation of culture and processing conditions. Cells Tissues Organs 197:360-71
Hadidi, Pasha; Athanasiou, Kyriacos A (2013) Enhancing the mechanical properties of engineered tissue through matrix remodeling via the signaling phospholipid lysophosphatidic acid. Biochem Biophys Res Commun 433:133-8
Sanchez-Adams, Johannah; Athanasiou, Kyriacos A (2012) Biomechanics of meniscus cells: regional variation and comparison to articular chondrocytes and ligament cells. Biomech Model Mechanobiol 11:1047-56
Huey, Daniel J; Hu, Jerry C; Athanasiou, Kyriacos A (2012) Unlike bone, cartilage regeneration remains elusive. Science 338:917-21

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