Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA013353-23
Application #
2086135
Study Section
Radiation Study Section (RAD)
Project Start
1977-09-30
Project End
2001-03-31
Budget Start
1996-06-01
Budget End
1997-03-31
Support Year
23
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Song, C W; Shakil, A; Osborn, J L et al. (2009) Tumour oxygenation is increased by hyperthermia at mild temperatures. 1996. Int J Hyperthermia 25:91-5
Monzen, Hajime; Griffin, Robert J; Williams, Brent W et al. (2004) Study of arsenic trioxide-induced vascular shutdown and enhancement with radiation in solid tumor. Radiat Med 22:205-11
Griffin, R J; Monzen, H; Williams, B W et al. (2003) Arsenic trioxide induces selective tumour vascular damage via oxidative stress and increases thermosensitivity of tumours. Int J Hyperthermia 19:575-89
Griffin, Robert J; Williams, Brent W; Wild, Robert et al. (2002) Simultaneous inhibition of the receptor kinase activity of vascular endothelial, fibroblast, and platelet-derived growth factors suppresses tumor growth and enhances tumor radiation response. Cancer Res 62:1702-6
Song, C W; Park, H; Griffin, R J (2001) Improvement of tumor oxygenation by mild hyperthermia. Radiat Res 155:515-28
Park, H J; Lyons, J C; Ohtsubo, T et al. (2000) Cell cycle progression and apoptosis after irradiation in an acidic environment. Cell Death Differ 7:729-38
Griffin, R J; Ogawa, A; Song, C W (2000) A novel drug to reduce tumor perfusion: antitumor effect alone and with hyperthermia. Radiat Res 154:202-7
Ogawa, A; Griffin, R J; Song, C W (2000) Effect of a combination of mild-temperature hyperthermia and nicotinamide on the radiation response of experimental tumors. Radiat Res 153:327-31
Park, H; Lyons, J C; Griffin, R J et al. (2000) Apoptosis and cell cycle progression in an acidic environment after irradiation. Radiat Res 153:295-304
Shakil, A; Osborn, J L; Song, C W (1999) Changes in oxygenation status and blood flow in a rat tumor model by mild temperature hyperthermia. Int J Radiat Oncol Biol Phys 43:859-65

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