The techniques of nuclear magnetic resonance zeugmatographic imaging are to be further developed, with special reference the cancer detection and diagnosis. The long-term objectives are to increase the usefulness of such techniques and to extend them into new areas. Specifically, this application has the following specific aims: 1. To continue the development of quantitative 3-demensional relaxation time imaging of surgical specimens so as to correlate such tissue properties with pathological changes observed on biopsy and surgical specimens, and eventually with pre- and post-operative patients. 2. To develop new mathematical approaches, computer algorithms, and imaging apparatus for spectroscopic imaging, stochastic imaging in rotating gradients, imaging with single surface coils, and the use of off-resonance irradiation for contrast enhancement. 3. To further develop effective relaxation time display methods.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA015300-12
Application #
3164142
Study Section
(SSS)
Project Start
1976-12-01
Project End
1987-01-31
Budget Start
1985-12-01
Budget End
1987-01-31
Support Year
12
Fiscal Year
1986
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Type
Schools of Arts and Sciences
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Mendonca Dias, M H; Lauterbur, P C (1986) Ferromagnetic particles as contrast agents for magnetic resonance imaging of liver and spleen. Magn Reson Med 3:328-30