Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA020807-11S1
Application #
3165387
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1989-01-01
Project End
1991-11-30
Budget Start
1989-01-01
Budget End
1990-11-30
Support Year
11
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Rutgers University
Department
Type
Schools of Pharmacy
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Wall, K L; Gao, W; Qu, W et al. (1992) Food restriction increases detoxification of polycyclic aromatic hydrocarbons in the rat. Carcinogenesis 13:519-23
Kwei, G Y; Zaleski, J; Irwin, S E et al. (1992) Conjugation of benzo(a)pyrene 7,8-dihydrodiol-9,10-epoxide in infant Swiss-Webster mice. Cancer Res 52:1639-42
Irwin, S E; Kwei, G Y; Blackburn, G R et al. (1992) Mutagenicity of benzo(a)pyrenyl-1-sulfate in the Ames test. Environ Mol Mutagen 19:253-8
Kauffman, F C; Whittaker, M; Anundi, I et al. (1991) Futile cycling of a sulfate conjugate by isolated hepatocytes. Mol Pharmacol 39:414-20
Zhong, Z; Kauffman, F C; Thurman, R G (1991) Inhibition of glucuronidation of benzo(a)pyrene phenols by long-chain fatty acids. Cancer Res 51:4511-5
Kwei, G Y; Zaleski, J; Thurman, R G et al. (1991) Enzyme activities associated with carcinogen metabolism in liver and nonhepatic tissues of rats maintained on high fat and food-restricted diets. J Nutr 121:131-7
Wall, K L; Gao, W S; te Koppele, J M et al. (1991) The liver plays a central role in the mechanism of chemical carcinogenesis due to polycyclic aromatic hydrocarbons. Carcinogenesis 12:783-6
Zaleski, J; Kwei, G Y; Thurman, R G et al. (1991) Suppression of benzo[a]pyrene metabolism by accumulation of triacylglycerols in rat hepatocytes: effect of high-fat and food-restricted diets. Carcinogenesis 12:2073-9
Wu, Y R; Kauffman, F C; Qu, W et al. (1990) Unique role of oxygen in regulation of hepatic monooxygenation and glucuronidation. Mol Pharmacol 38:128-33
Kauffman, F C; Whittaker, M; Badr, M Z et al. (1990) Effect of epinephrine on glycogen phosphorylase-alpha in various preparations of rat liver. Comp Biochem Physiol B 96:113-8

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