Bruceantin (NSC-165563) is a member of the quassinoid family of diterpenes that has been found to have significant anti-tumor and anti-leukemic properties. The goal of this research project is to develop an efficient total synthesis of bruceantin, so that modified versions of the drug may be prepared for physiological evaluation.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA021163-09
Application #
3165479
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1977-09-30
Project End
1987-03-31
Budget Start
1986-04-01
Budget End
1987-03-31
Support Year
9
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Type
Schools of Arts and Sciences
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704