Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA021289-11S1
Application #
3165516
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1977-09-01
Project End
1991-06-30
Budget Start
1988-07-01
Budget End
1989-06-30
Support Year
11
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Michigan State University
Department
Type
Schools of Osteopathy
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
McCormick, J J; Maher, V M (1994) Analysis of the multistep process of carcinogenesis using human fibroblasts. Risk Anal 14:257-63
Yang, D; Louden, C; Reinhold, D S et al. (1992) Malignant transformation of human fibroblast cell strain MSU-1.1 by (+-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo [a]pyrene. Proc Natl Acad Sci U S A 89:2237-41
Miller, M J; Maher, V M; McCormick, J J (1992) Quantitative two-dimensional gel electrophoresis analysis of human fibroblasts transformed by ras oncogenes. Electrophoresis 13:862-70
Jankun, J; Maher, V M; McCormick, J J (1991) Malignant transformation of human fibroblasts correlates with increased activity of receptor-bound plasminogen activator. Cancer Res 51:1221-6
Morgan, T L; Yang, D J; Fry, D G et al. (1991) Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogene. Exp Cell Res 197:125-36
Maher, V M; Yang, J L; Chen, R H et al. (1991) Use of PCR amplification of cDNA to study mechanisms of human cell mutagenesis and malignant transformation. Environ Mol Mutagen 18:239-44
Wilson, D M; Yang, D J; Dillberger, J E et al. (1990) Malignant transformation of human fibroblasts by a transfected N-ras oncogene. Cancer Res 50:5587-93
Fry, D G; Milam, L D; Dillberger, J E et al. (1990) Malignant transformation of an infinite life span human fibroblast cell strain by transfection with v-Ki-ras. Oncogene 5:1415-8
Fox, T R; Schumann, A M; Watanabe, P G et al. (1990) Mutational analysis of the H-ras oncogene in spontaneous C57BL/6 x C3H/He mouse liver tumors and tumors induced with genotoxic and nongenotoxic hepatocarcinogens. Cancer Res 50:4014-9
McCormick, J J; Fry, D G; Hurlin, P J et al. (1990) Malignant transformation of human fibroblasts by oncogene transfection or carcinogen treatment. Prog Clin Biol Res 340D:195-205

Showing the most recent 10 out of 28 publications