Canine Lung Cancer Model for Surgical Research

Benfield, John R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 2R01CA026529-08
• Application #: 3167341
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Project Start: 1988-02-01
• Project End: 1988-09-29
• Budget Start: 1988-02-01
• Budget End: 1988-09-29
• Support Year: 8
• Fiscal Year: 1988

Institution

• Name: Los Angeles County Harbor-UCLA Medical Center
• City: Torrance
• State: CA
• Country: United States
• Zip Code: 90509

Publications

Ten Have-Opbroek, A A; Benfield, J R; Hammond, W G et al. (1994) In favour of an oncofoetal concept of bronchogenic carcinoma development. Histol Histopathol 9:375-84

TenHave-Opbroek, A A; Hammond, W G; Benfield, J R et al. (1993) Expression of alveolar type II cell markers in acinar adenocarcinomas and adenoid cystic carcinomas arising from segmental bronchi. A study in a heterotopic bronchogenic carcinoma model in dogs. Am J Pathol 142:1251-64

Benfield, J R; Hammond, W G (1992) Bronchial and pulmonary carcinogenesis at focal sites in dogs and hamsters. Cancer Res 52:2687s-2693s

Hammond, W G; Benfield, J R; Teplitz, R L (1991) Metastatic behaviour of canine lung carcinoma in autochthonous and xenotransplant hosts. Clin Exp Metastasis 9:567-77

Hammond, W G; Teplitz, R L; Benfield, J R (1991) Variable regression of experimental bronchial preneoplasia during carcinogenesis. J Thorac Cardiovasc Surg 101:800-6

Hammond, W G; Benfield, J R; Teplitz, R L (1991) Metastases from fresh human non-small cell lung cancers propagated in nude mice. Cancer Lett 61:53-60

Ten Have-Opbroek, A A; Hammond, W G; Benfield, J R (1990) Bronchiolo-alveolar regions in adenocarcinoma arising from canine segmental bronchus. Cancer Lett 55:177-82

Hammond, W G; Yellin, A; Gabriel, A et al. (1990) Quantitative DNA alterations during 5-azacytidine-induced differential modulation of benzo(a)pyrene carcinogenesis in hamster bronchi. Cancer Commun 2:135-44

Hammond, W G; Yellin, A; Gabriel, A et al. (1990) Effects of 5-azacytidine in Syrian golden hamsters: toxicity, tumorigenicity, and differential modulation of bronchial carcinogenesis. Exp Mol Pathol 53:34-51

Derrick, M J; Hammond, W G; Pak, H Y et al. (1988) Non-small cell lung cancer in autogenous subcutaneous bronchial grafts in dogs. J Thorac Cardiovasc Surg 95:562-71