Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA030515-03S1
Application #
3169281
Study Section
Experimental Immunology Study Section (EI)
Project Start
1982-08-01
Project End
1985-08-31
Budget Start
1984-07-01
Budget End
1985-08-31
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Connor, M J; Sidell, N (1997) Retinoic acid synthesis in normal and Alzheimer diseased brain and human neural cells. Mol Chem Neuropathol 30:239-52
Saxon, A; Max, E E; Diaz-Sanchez, D et al. (1995) Alternative RNA of epsilon transcripts produces mRNAs encoding two membrane and four secreted IgE isoforms. Int Arch Allergy Immunol 107:45-7
Sidell, N; Wada, R; Han, G et al. (1995) Phenylacetate synergizes with retinoic acid in inducing the differentiation of human neuroblastoma cells. Int J Cancer 60:507-14
Han, G; Chang, B; Connor, M J et al. (1995) Enhanced potency of 9-cis versus all-trans-retinoic acid to induce the differentiation of human neuroblastoma cells. Differentiation 59:61-9
Saxon, A; Keld, B; Diaz-Sanchez, D et al. (1995) B cells from a distinct subset of patients with common variable immunodeficiency (CVID) have increased CD95 (Apo-1/fas), diminished CD38 expression, and undergo enhanced apoptosis. Clin Exp Immunol 102:17-25
Zhang, K; Max, E E; Cheah, H K et al. (1994) Complex alternative RNA splicing of epsilon-immunoglobulin transcripts produces mRNAs encoding four potential secreted protein isoforms. J Biol Chem 269:456-62
Wuarin, L; Chang, B; Wada, R et al. (1994) Retinoic acid up-regulates nuclear retinoic acid receptor-alpha expression in human neuroblastoma cells. Int J Cancer 56:840-5
Bhatti, L; Sidell, N (1994) Transcriptional regulation by retinoic acid of interleukin-2 alpha receptors in human B cells. Immunology 81:273-9
Sidell, N; Chang, B; Bhatti, L (1993) Upregulation by retinoic acid of interleukin-2-receptor mRNA in human T lymphocytes. Cell Immunol 146:28-37
Saxon, A; Keld, B; Braun, J et al. (1993) Long-term administration of 13-cis retinoic acid in common variable immunodeficiency: circulating interleukin-6 levels, B-cell surface molecule display, and in vitro and in vivo B-cell antibody production. Immunology 80:477-87

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