The cohort study is designed to measure the individual risks and benefits of menopausal estrogen therapy in terms of incident disease and mortality; to study whether longterm use of Vitamin A supplements alters risk to epithelial cancers; and to evaluate the possible risks and benefits associated with other 'health related' practices in older adults. Questionnaires will be mailed to all 19,800 residents of a retirement community in Orange County, California, requesting information on use of estrogen replacement therapy (women only), on use of vitamin supplements, and on other health-related practices, including cigarette smoking, alcohol consumption, exercise habits, intake of certain dietary nutrients or food items (Vitamin A and Vitamin C, coffee, artificial sweeteners) and use of periodic screening for certain chronic diseases. Non-respondents will be mailed three such questionnaires in all and then be contacted by telephone. In this way, we expect to identify a cohort of 14,000 persons. Follow-up will be maintained by annual recontact of each surviving cohort member; by routine ascertainment of death certificates from the Orange County Health Department, and by routine screening of disease indices of all local hospitals.
| Paganini-Hill, Annlia; Kawas, Claudia H; Corrada, María M (2018) Positive Mental Attitude Associated with Lower 35-Year Mortality: The Leisure World Cohort Study. J Aging Res 2018:2126368 |
| Corrada, María M; Hayden, Kathleen M; Paganini-Hill, Annlia et al. (2017) Age of onset of hypertension and risk of dementia in the oldest-old: The 90+ Study. Alzheimers Dement 13:103-110 |
| Paganini-Hill, Annlia; Kawas, Claudia H; Corrada, Maria M (2016) Lifestyle Factors and Dementia in the Oldest-old: The 90+ Study. Alzheimer Dis Assoc Disord 30:21-6 |
| Paganini-Hill, Annlia; Kawas, Claudia H; Corrada, María M (2015) Antioxidant vitamin intake and mortality: the Leisure World Cohort Study. Am J Epidemiol 181:120-6 |
| Paganini-Hill, Annlia; Ducey, Beverly; Hawk, Marian (2013) Responders versus nonresponders in a dementia study of the oldest old: the 90+ study. Am J Epidemiol 177:1452-8 |
| Paganini-Hill, Annlia (2012) Hypertension and dementia in the elderly: the leisure world cohort study. Int J Hypertens 2012:205350 |
| Paganini-Hill, Annlia; White, Stuart C; Atchison, Kathryn A (2012) Dentition, dental health habits, and dementia: the Leisure World Cohort Study. J Am Geriatr Soc 60:1556-63 |
| Paganini-Hill, Annlia; White, Stuart C; Atchison, Kathryn A (2011) Dental health behaviors, dentition, and mortality in the elderly: the leisure world cohort study. J Aging Res 2011:156061 |
| Paganini-Hill, Annlia (2011) Lifestyle practices and cardiovascular disease mortality in the elderly: the leisure world cohort study. Cardiol Res Pract 2011:983764 |
| Paganini-Hill, Annlia; Kawas, Claudia H; Corrada, María M (2011) Activities and mortality in the elderly: the Leisure World cohort study. J Gerontol A Biol Sci Med Sci 66:559-67 |
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