Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA036700-10S1
Application #
3174271
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1983-07-01
Project End
1994-06-30
Budget Start
1992-05-01
Budget End
1994-06-30
Support Year
10
Fiscal Year
1992
Total Cost
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206
Wade, W F; Ward, E D; Rosloniec, E F et al. (1994) Truncation of the A alpha chain of MHC class II molecules results in inefficient antigen presentation to antigen-specific T cells. Int Immunol 6:1457-65
Rosloniec, E F; Beard, K S; Freed, J H (1993) Functional analysis of the antigen binding region of an MHC class II molecule. Mol Immunol 30:491-501
Freed, J H; Marrack, P (1993) Tissue-specific expression of self peptides bound by major histocompatibility complex class II molecules. Chem Immunol 57:88-112
Newell, M K; VanderWall, J; Beard, K S et al. (1993) Ligation of major histocompatibility complex class II molecules mediates apoptotic cell death in resting B lymphocytes. Proc Natl Acad Sci U S A 90:10459-63
Rosloniec, E F; Vitez, L J; Buus, S et al. (1990) MHC class II-derived peptides can bind to class II molecules, including self molecules, and prevent antigen presentation. J Exp Med 171:1419-30
Wade, W F; Freed, J H; Edidin, M (1989) Translational diffusion of class II major histocompatibility complex molecules is constrained by their cytoplasmic domains. J Cell Biol 109:3325-31
Rosloniec, E F; Vitez, L J; Beck, B N et al. (1989) I-Ak polymorphisms define a functionally dominant region for the presentation of hen egg lysozyme peptides. J Immunol 143:50-8
Wade, W F; Chen, Z Z; Maki, R et al. (1989) Altered I-A protein-mediated transmembrane signaling in B cells that express truncated I-Ak protein. Proc Natl Acad Sci U S A 86:6297-301
Rosloniec, E F; Gay, D; Freed, J H (1989) Epitopic analysis by anti-I-Ak monoclonal antibodies of I-Ak-restricted presentation of lysozyme peptides. J Immunol 142:4176-83
Newell, M K; Justement, L B; Miles, C R et al. (1988) Biochemical characterization of proteins that co-purify with class II antigens of the murine MHC. J Immunol 140:1930-8

Showing the most recent 10 out of 12 publications