Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA038192-06
Application #
2089526
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1987-02-01
Project End
1997-01-31
Budget Start
1995-04-25
Budget End
1997-01-31
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Tulane University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Strobel, S M; Szklarz, G D; He, Y et al. (1999) Identification of selective mechanism-based inactivators of cytochromes P-450 2B4 and 2B5, and determination of the molecular basis for differential susceptibility. J Pharmacol Exp Ther 290:445-51
Alexander, D L; Zhang, L; Foroozesh, M et al. (1999) Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity. Toxicol Appl Pharmacol 161:123-39
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Beresford, A P; Taylor, R J; Ashcroft, J A et al. (1996) Expression of human cytochrome P4501A1 (CYP1A1) in Saccharomyces cerevisiae inhibits cell division. Xenobiotica 26:1013-23
Roberts, E S; Hopkins, N E; Zaluzec, E J et al. (1995) Mechanism-based inactivation of cytochrome P450 2B1 by 9-ethynylphenanthrene. Arch Biochem Biophys 323:295-302
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