Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA040064-08S1
Application #
2090096
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1985-07-01
Project End
1995-03-31
Budget Start
1993-04-01
Budget End
1995-03-31
Support Year
8
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Ethier, S P; Kokeny, K E; Ridings, J W et al. (1996) erbB family receptor expression and growth regulation in a newly isolated human breast cancer cell line. Cancer Res 56:899-907
Ethier, S P; Langton, B C; Dilts, C A (1996) Growth factor-independent proliferation of rat mammary carcinoma cells by autocrine secretion of neu-differentiation factor/heregulin and transforming growth factor-alpha. Mol Carcinog 15:134-43
Ram, T G; Ethier, S P (1996) Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplifi Cell Growth Differ 7:551-61
Ethier, S P; Mahacek, M L; Gullick, W J et al. (1993) Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media. Cancer Res 53:627-35
Mahacek, M L; Beer, D G; Frank, T S et al. (1993) Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node. Breast Cancer Res Treat 28:267-76
Ethier, S P; Moorthy, R; Dilts, C A (1991) Secretion of an epidermal growth factor-like growth factor by epidermal growth factor-independent rat mammary carcinoma cells. Cell Growth Differ 2:593-602
Ethier, S P; Moorthy, R (1991) Multiple growth factor independence in rat mammary carcinoma cells. Breast Cancer Res Treat 18:73-81
Lowney, P; Corral, J; Detmer, K et al. (1991) A human Hox 1 homeobox gene exhibits myeloid-specific expression of alternative transcripts in human hematopoietic cells. Nucleic Acids Res 19:3443-9
Ethier, S P; Van de Velde, R M (1990) Secretion of a TGF-beta-like growth inhibitor by normal rat mammary epithelial cells in vitro. J Cell Physiol 142:15-20
Ethier, S P; Chiodino, C; Jones, R F (1990) Role of growth factor synthesis in the acquisition of insulin/insulin-like growth factor I independence in rat mammary carcinoma cells. Cancer Res 50:5351-7

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