Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA040440-08
Application #
3180380
Study Section
Experimental Virology Study Section (EVR)
Project Start
1992-02-01
Project End
1993-08-31
Budget Start
1992-02-01
Budget End
1993-08-31
Support Year
8
Fiscal Year
1991
Total Cost
Indirect Cost
Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105
Srinivas, R V; Rui, Z; Compans, R W (1992) A carboxy-terminal mutant spleen focus-forming virus (SFFV) envelope glycoprotein is transport-competent, but non-leukemogenic. Virus Res 26:57-69
Srinivas, R V; Tucker, S P; Kilpatrick, D R et al. (1992) A 585-bp deletion found in the spleen focus-forming virus (SFFV) env gene is responsible for the defective intracellular transport of SFFV gp52. Virology 188:181-92
Srinivas, R V; Venkatachalapathi, Y V; Rui, Z et al. (1991) Inhibition of virus-induced cell fusion by apolipoprotein A-I and its amphipathic peptide analogs. J Cell Biochem 45:224-37
Tucker, S P; Srinivas, R V; Compans, R W (1991) Molecular domains involved in oligomerization of the Friend murine leukemia virus envelope glycoprotein. Virology 185:710-20
Srinivas, R V; Kilpatrick, D R; Tucker, S et al. (1991) The hydrophobic membrane-spanning sequences of the gp52 glycoprotein are required for the pathogenicity of Friend spleen focus-forming virus. J Virol 65:5272-80
Srinivas, R V; Birkedal, B; Owens, R J et al. (1990) Antiviral effects of apolipoprotein A-I and its synthetic amphipathic peptide analogs. Virology 176:48-57
Owens, B J; Anantharamaiah, G M; Kahlon, J B et al. (1990) Apolipoprotein A-I and its amphipathic helix peptide analogues inhibit human immunodeficiency virus-induced syncytium formation. J Clin Invest 86:1142-50
Powell Jr, T J; Gaupp, B; Epps, J M et al. (1989) Isotype distribution and specificity of the antibody response to primary Moloney murine sarcoma virus infection in BALB/c mice. Viral Immunol 2:89-101
Kilpatrick, D R; Srinivas, R V; Compans, R W (1989) The spleen focus-forming virus envelope glycoprotein is defective in oligomerization. J Biol Chem 264:10732-7
Kilpatrick, D R; Srinivas, R V; Compans, R W (1988) Expression of the spleen focus-forming virus envelope gene in a polarized epithelial cell line. Virology 164:547-50

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