Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA043297-04A1S1
Application #
3185462
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1986-09-01
Project End
1995-02-28
Budget Start
1990-04-01
Budget End
1991-02-28
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Strum, J C; Small, G W; Pauig, S B et al. (1994) 1-beta-D-Arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells. J Biol Chem 269:15493-7
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Strum, J C; Daniel, L W (1993) Identification of a lysophospholipase C that may be responsible for the biosynthesis of choline plasmalogens by Madin-Darby canine kidney cells. J Biol Chem 268:25500-8
Daniel, L W; Huang, C; Strum, J C et al. (1993) Phospholipase D hydrolysis of choline phosphoglycerides is selective for the alkyl-linked subclass of Madin-Darby canine kidney cells. J Biol Chem 268:21519-26
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Marasco Jr, C J; Piantadosi, C; Meyer, K L et al. (1990) Synthesis and biological activity of novel quaternary ammonium derivatives of alkylglycerols as potent inhibitors of protein kinase C. J Med Chem 33:985-92
Chabot, M C; Wykle, R L; Modest, E J et al. (1989) Correlation of ether lipid content of human leukemia cell lines and their susceptibility to 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine. Cancer Res 49:4441-5
Ishaq, K S; Capobianco, M; Piantadosi, C et al. (1989) Synthesis and biological evaluation of ether-linked derivatives of phosphatidylinositol. Pharm Res 6:216-24
Marx, M H; Piantadosi, C; Noseda, A et al. (1988) Synthesis and evaluation of neoplastic cell growth inhibition of 1-N-alkylamide analogues of glycero-3-phosphocholine. J Med Chem 31:858-63

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