Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA043783-05S1
Application #
3186121
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1986-03-05
Project End
1994-02-28
Budget Start
1990-03-01
Budget End
1991-02-28
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Ciaccio, P J; Stuart, J E; Tew, K D (1993) Overproduction of a 37.5-kDa cytosolic protein structurally related to prostaglandin F synthase in ethacrynic acid-resistant human colon cells. Mol Pharmacol 43:845-53
Speicher, L A; Barone, L; Tew, K D (1992) Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines. Cancer Res 52:4433-40
Tew, K D; Glusker, J P; Hartley-Asp, B et al. (1992) Preclinical and clinical perspectives on the use of estramustine as an antimitotic drug. Pharmacol Ther 56:323-39
Sheridan, V R; Speicher, L A; Tew, K D (1991) The effects of estramustine on metaphase and anaphase in DU 145 prostatic carcinoma cells. Eur J Cell Biol 54:268-76
Stearns, M E; Tew, K D (1988) Estramustine binds MAP-2 to inhibit microtubule assembly in vitro. J Cell Sci 89 ( Pt 3):331-42
Stearns, M E; Wang, M; Tew, K D et al. (1988) Estramustine binds a MAP-1-like protein to inhibit microtubule assembly in vitro and disrupt microtubule organization in DU 145 cells. J Cell Biol 107:2647-56
Tew, K D; Clapper, M L; Greenberg, R E et al. (1987) Glutathione S-transferases in human prostate. Biochim Biophys Acta 926:8-15