Brooks, Sam C; Skafar, Debra F (2004) From ligand structure to biological activity: modified estratrienes and their estrogenic and antiestrogenic effects in MCF-7 cells. Steroids 69:401-18
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Davis, M D; VanderKuur, J A; Brooks, S C (1999) Ligand structure influences autologous downregulation of estrogen receptor-alpha messenger RNA. J Steroid Biochem Mol Biol 70:27-37
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Schwartz, J A; Liu, G; Brooks, S C (1998) Genistein-mediated attenuation of tamoxifen-induced antagonism from estrogen receptor-regulated genes. Biochem Biophys Res Commun 253:38-43
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Schwartz, J A; Brooks, S C (1997) Neutral mutations to three acidic AF2 residues in the mouse estrogen receptor confer agonist activity to A-ring isomers of estradiol. J Steroid Biochem Mol Biol 62:173-84
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Wiese, T E; Polin, L A; Palomino, E et al. (1997) Induction of the estrogen specific mitogenic response of MCF-7 cells by selected analogues of estradiol-17 beta: a 3D QSAR study. J Med Chem 40:3659-69
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Pilat, M J; Christman, J K; Brooks, S C (1996) Characterization of the estrogen receptor transfected MCF10A breast cell line 139B6. Breast Cancer Res Treat 37:253-66
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Palomino, E; Heeg, M J; Pilat, M J et al. (1996) Crystal structure, receptor binding, and gene regulation of 2- and 4-nitroestradiols. Steroids 61:670-6
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Wiese, T E; Dukes, D; Brooks, S C (1995) A molecular modeling analysis of diethylstilbestrol conformations and their similarity to estradiol-17 beta. Steroids 60:802-8
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Davis, M D; Butler, W B; Brooks, S C (1995) Induction of tissue plasminogen activator mRNA and activity by structurally altered estrogens. J Steroid Biochem Mol Biol 52:421-30
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Christman, J K; Nehls, S; Polin, L et al. (1995) Relationship between estrogen structure and conformational changes in estrogen receptor/DNA complexes. J Steroid Biochem Mol Biol 54:201-10
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