Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA046812-08
Application #
2092313
Study Section
Experimental Immunology Study Section (EI)
Project Start
1988-02-01
Project End
1997-01-31
Budget Start
1995-03-10
Budget End
1997-01-31
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Daniels, B F; Nakamura, M C; Rosen, S D et al. (1994) Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain. Immunity 1:785-92
Yokoyama, W M; Seaman, W E (1993) The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annu Rev Immunol 11:613-35
Bell, G M; Seaman, W E; Niemi, E C et al. (1992) The OX-44 molecule couples to signaling pathways and is associated with CD2 on rat T lymphocytes and a natural killer cell line. J Exp Med 175:527-36
Ryan, J C; Turck, J; Niemi, E C et al. (1992) Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules. J Immunol 149:1631-5
Goldfien, R D; Seaman, W E; Hempel, W M et al. (1991) Divergent regulation of phospholipase C-alpha and phospholipase C-gamma transcripts during activation of a human T cell line. J Immunol 146:3703-8
Seaman, W E; Niemi, E C; Stark, M R et al. (1991) Molecular cloning of gp42, a cell-surface molecule that is selectively induced on rat natural killer cells by interleukin 2: glycolipid membrane anchoring and capacity for transmembrane signaling. J Exp Med 173:251-60
Yokoyama, W M; Ryan, J C; Hunter, J J et al. (1991) cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6. J Immunol 147:3229-36
Ryan, J C; Niemi, E C; Goldfien, R D et al. (1991) NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium. J Immunol 147:3244-50
Imboden, J B; Bell, G; Seaman, W E (1991) Characterization of signal-transducing molecules on natural killer cells. Biochem Soc Trans 19:265-8
Imboden, J B; Eriksson, E C; McCutcheon, M et al. (1989) Identification and characterization of a cell-surface molecule that is selectively induced on rat lymphokine-activated killer cells. J Immunol 143:3100-3