Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA047912-02
Application #
3191741
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1989-01-05
Project End
1991-08-31
Budget Start
1989-01-13
Budget End
1989-08-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Oakland University
Department
Type
Schools of Arts and Sciences
DUNS #
City
Rochester
State
MI
Country
United States
Zip Code
48309
Bronstein, J C; Bull, A W (1997) Substrate specificity and characterization of partially purified rat liver 13-hydroxyoctadecadienoic acid (13-HODE) dehydrogenase. Arch Biochem Biophys 348:219-25
Bull, A W; Bronstein, J C; Earles, S M et al. (1996) Formation of adducts between 13-oxooctadecadienoic acid (13-OXO) and protein-derived thiols, in vivo and in vitro. Life Sci 58:2355-65
Bull, A W; Earles, S M; Blackburn, M L (1993) Regulation of the induction of ornithine decarboxylase in short-term rat colon organ culture by dexamethasone and 13-hydroxyoctadecadienoic acid (13-HODE). Life Sci 53:377-85
Brar, R S; Bull, A W (1993) Effect of alkyl sulfides on diazomethane-induced methylation of DNA in vitro. Cancer Lett 73:121-5
Bronstein, J C; Bull, A W (1993) The correlation between 13-hydroxyoctadecadienoate dehydrogenase (13-HODE dehydrogenase) and intestinal cell differentiation. Prostaglandins 46:387-95
Desai, T K; Parikh, N; Bronstein, J C et al. (1992) Failure of rectal ornithine decarboxylase to identify adenomatous polyp status. Gastroenterology 103:1562-7
Earles, S M; Bronstein, J C; Winner, D L et al. (1991) Metabolism of oxidized linoleic acid: characterization of 13-hydroxyoctadecadienoic acid dehydrogenase activity from rat colonic tissue. Biochim Biophys Acta 1081:174-80
Bull, A W; Earles, S M; Bronstein, J C (1991) Metabolism of oxidized linoleic acid: distribution of activity for the enzymatic oxidation of 13-hydroxyoctadecadienoic acid to 13-oxooctadecadienoic acid in rat tissues. Prostaglandins 41:43-50
Bull, A W; Bronstein, J C (1990) Production of unsaturated carbonyl compounds during metabolism of hydroperoxy fatty acids by colonic homogenates. Carcinogenesis 11:1699-704