Poly-Adp-Ribose and Repair of Radiation Induced Damage

Stamato, Thomas Dominic

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA048636-03
• Application #: 3192530
• Study Section: Radiation Study Section (RAD)
• Project Start: 1988-05-01
• Project End: 1990-06-02
• Budget Start: 1990-05-01
• Budget End: 1990-06-02
• Support Year: 3
• Fiscal Year: 1990

Institution

• Name: Wistar Institute
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Witmer, M V; Aboul-Ela, N; Jacobson, M K et al. (1994) Increased sensitivity to DNA-alkylating agents in CHO mutants with decreased poly(ADP-ribose) polymerase activity. Mutat Res 314:249-60

Iliakis, G E; Metzger, L; Denko, N et al. (1991) Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. Int J Radiat Biol 59:321-41

Elia, M C; Motyka, L E; Stamato, T D (1991) Electrotransfer of [32P]NAD allows labeling of ADP-ribosylated proteins in intact Chinese hamster ovary cells. Anal Biochem 192:329-33

MacLaren, R A; Witmer, M V; Richardson, E et al. (1990) Isolation of Chinese hamster ovary cells with reduced poly(ADP-ribose) polymerase activity. Mutat Res 231:265-74