Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA049935-04
Application #
3194293
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1989-09-01
Project End
1993-08-31
Budget Start
1992-04-27
Budget End
1992-08-31
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
Organized Research Units
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
McCabe Jr, M J; Singh, K P; Reiners Jr, J J (2001) Low level lead exposure in vitro stimulates the proliferation and expansion of alloantigen-reactive CD4(high) T cells. Toxicol Appl Pharmacol 177:219-31
McCabe Jr, M J; Singh, K P; Reiners Jr, J J (1999) Lead intoxication impairs the generation of a delayed type hypersensitivity response. Toxicology 139:255-64
Reiners Jr, J J; Singh, K P; Yoon, H L et al. (1997) Transplantation analyses of the immunogenicity of epidermal tumors generated in murine skin two-stage carcinogenesis protocols. Mol Carcinog 20:48-57
Reiners Jr, J J; Singh, K P (1997) Susceptibility of 129/SvEv mice in two-stage carcinogenesis protocols to 12-O-tetradecanoylphorbol-13-acetate promotion. Carcinogenesis 18:593-7
Yoon, H L; Singh, K P; Ratner, S et al. (1996) Phorbol ester effects on splenic lymphocyte composition and cytotoxic T cell activities of SSIN mice: a strain deficient in CD8+ T cells. Carcinogenesis 17:2617-24
Singh, K P; Yoon, H L; Ratner, S et al. (1996) Modulation of the development of humoral immunity by topically applied acetone, ethanol, and 12-O-tetradecanoylphorbol-13-acetate. Fundam Appl Toxicol 33:129-39
Kodari, E; Pavone, A; Reiners Jr, J J (1993) Differential modulation of contact hypersensitivity and delayed hypersensitivity reactions by topical application of 12-O-tetradecanoylphorbol-13-acetate. Immunopharmacol Immunotoxicol 15:639-47
Reiners Jr, J J; Cantu, A; Thai, G et al. (1993) Differential co-promoting activities of alpha, beta and gamma interferons in the murine skin two-stage carcinogenesis model. Carcinogenesis 14:367-72
Reiners Jr, J J; Pavone, A; Maldve, R et al. (1993) 12-O-tetradecanoylphorbol-13-acetate-mediated systemic co-promotion in the murine skin multistage carcinogenesis protocol. Carcinogenesis 14:411-5
Gimenez-Conti, I B; Bianchi, A B; Fischer, S M et al. (1992) Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice. Cancer Res 52:3432-5

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