Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA050174-05
Application #
2093633
Study Section
Radiation Study Section (RAD)
Project Start
1990-12-06
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Holden, S A; Emi, Y; Kakeji, Y et al. (1997) Host distribution and response to antitumor alkylating agents of EMT-6 tumor cells from subcutaneous tumor implants. Cancer Chemother Pharmacol 40:87-93
Teicher, B A; Holden, S A; Ara, G et al. (1996) Transforming growth factor-beta in in vivo resistance. Cancer Chemother Pharmacol 37:601-9
Bubley, G J; Xu, J; Kupiec, N et al. (1996) Effect of DNA conformation on cisplatin adduct formation. Biochem Pharmacol 51:717-21
Ara, G; Teicher, B A (1996) Cyclooxygenase and lipoxygenase inhibitors in cancer therapy. Prostaglandins Leukot Essent Fatty Acids 54:3-16
Teicher, B A; Holden, S A; Ara, G et al. (1996) Comparison of several antiangiogenic regimens alone and with cytotoxic therapies in the Lewis lung carcinoma. Cancer Chemother Pharmacol 38:169-77
Teicher, B A; Holden, S A; Ara, G et al. (1995) Whole-body hyperthermia and lonidamine as adjuvant therapy to treatment with cisplatin with or without local radiation in mouse bearing the Lewis lung carcinoma. Int J Hyperthermia 11:637-45
Teicher, B A; Holden, S A; Dupuis, N P et al. (1995) Potentiation of cytotoxic therapies by TNP-470 and minocycline in mice bearing EMT-6 mammary carcinoma. Breast Cancer Res Treat 36:227-36
Kusumoto, T; Holden, S A; Ara, G et al. (1995) Hyperthermia and platinum complexes: time between treatments and synergy in vitro and in vivo. Int J Hyperthermia 11:575-86
Ara, G; Kusumoto, T; Korbut, T T et al. (1994) cis-Diamminedichloroplatinum(II) resistant human tumor cell lines are collaterally sensitive to PtCl4(Rh-123)2: evidence for mitochondrial involvement. Cancer Res 54:1497-502
Teicher, B A; Schwartz, J L; Holden, S A et al. (1994) In vivo modulation of several anticancer agents by beta-carotene. Cancer Chemother Pharmacol 34:235-41

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