This application is a competing renewal. The original project concerned new fast magnetic resonance imaging (MRI) techniques for improved diagnosis of abdominal tumors. Significant progress was made in developing several fast-scan methods that produce high-quality T2-weighted abdominal images in a breath-hold. The focus of this competing renewal is on new MR methods that take the next step beyond tumor detection---the guidance of tumor biopsies and other interventional procedures using MR. The project title has been modified to reflect this change in focus.
The aims of this project are to 1) design and implement a real-time, interactive (RTI) MRI system tailored for interventional procedures, 2) develop and integrate into the RTI system new sequences that provide useful image contrast for interventional procedures; and 3) evaluate this new MR interventional system on phantoms and patients. The research plan includes substantial technical development of a versatile RTI MRI platform, studies of improved MR acquisition methods (e.g., steady-state free precession, fast spin echo, and color flow), and systematic tests to validate the performance of the resultant system. A research team with extensive technical and clinical expertise has been assembled for this project. This expertise, along with the state-of-the-art scanners available, make Stanford University an ideal environment to carry out this project.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA050948-08
Application #
6375854
Study Section
Diagnostic Imaging Study Section (DMG)
Program Officer
Farahani, Keyvan
Project Start
1990-01-04
Project End
2003-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
8
Fiscal Year
2001
Total Cost
$295,919
Indirect Cost
Name
Stanford University
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
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