Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA051802-06A1
Application #
2094389
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1990-04-15
Project End
2000-05-31
Budget Start
1996-08-01
Budget End
1997-05-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Dermatology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Subbarayan, Murugesan; Hafeli, Urs O; Feyes, Denise K et al. (2003) A simplified method for preparation of 99mTc-annexin V and its biologic evaluation for in vivo imaging of apoptosis after photodynamic therapy. J Nucl Med 44:650-6
Wang, Steven I; Mukhtar, Hasan (2002) A high-efficiency translational control element with potential for cancer gene therapy. Int J Oncol 20:1269-74
Ahmad, N; Kalka, K; Mukhtar, H (2001) In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy. Oncogene 20:2314-7
Azizuddin, K; Kalka, K; Chiu, S M et al. (2001) Recombinant human tumor necrosis factor alpha does not potentiate cell killing after photodynamic therapy with a silicon phthalocyanine in A431 human epidermoid carcinoma cells. Int J Oncol 18:411-5
Srivastava, M; Ahmad, N; Gupta, S et al. (2001) Involvement of Bcl-2 and Bax in photodynamic therapy-mediated apoptosis. Antisense Bcl-2 oligonucleotide sensitizes RIF 1 cells to photodynamic therapy apoptosis. J Biol Chem 276:15481-8
Elmets, C A; Singh, D; Tubesing, K et al. (2001) Cutaneous photoprotection from ultraviolet injury by green tea polyphenols. J Am Acad Dermatol 44:425-32
Katiyar, S K; Mukhtar, H (2001) Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. J Leukoc Biol 69:719-26
Kalka, K; Merk, H; Mukhtar, H (2000) Photodynamic therapy in dermatology. J Am Acad Dermatol 42:389-413; quiz 414-6
Ahmad, N; Gupta, S; Feyes, D K et al. (2000) Involvement of Fas (APO-1/CD-95) during photodynamic-therapy-mediated apoptosis in human epidermoid carcinoma A431 cells. J Invest Dermatol 115:1041-6
Whitacre, C M; Feyes, D K; Satoh, T et al. (2000) Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice. Clin Cancer Res 6:2021-7

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