Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA052515-05
Application #
2094789
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1990-12-04
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Ito, C Y; Adey, N; Bautch, V L et al. (1995) Structure and evolution of the human IKBA gene. Genomics 29:490-5
Toth, C R; Hostutler, R F; Baldwin Jr, A S et al. (1995) Members of the nuclear factor kappa B family transactivate the murine c-myb gene. J Biol Chem 270:7661-71
Gualberto, A; Hixon, M L; Finco, T S et al. (1995) A proliferative p53-responsive element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeat. Mol Cell Biol 15:3450-9
Gualberto, A; Baldwin Jr, A S (1995) p53 and Sp1 interact and cooperate in the tumor necrosis factor-induced transcriptional activation of the HIV-1 long terminal repeat. J Biol Chem 270:19680-3
Scheinman, R I; Cogswell, P C; Lofquist, A K et al. (1995) Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270:283-6
Beg, A A; Baldwin Jr, A S (1994) Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor. Oncogene 9:1487-92
Finco, T S; Beg, A A; Baldwin Jr, A S (1994) Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors. Proc Natl Acad Sci U S A 91:11884-8
Ito, C Y; Kazantsev, A G; Baldwin Jr, A S (1994) Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha. Nucleic Acids Res 22:3787-92
Beg, A A; Finco, T S; Nantermet, P V et al. (1993) Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation. Mol Cell Biol 13:3301-10
Kowalik, T F; Wing, B; Haskill, J S et al. (1993) Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infection. Proc Natl Acad Sci U S A 90:1107-11

Showing the most recent 10 out of 19 publications