Tumor Suppressor Genes and Angiogenesis

Bouck, Noel P.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA052750-07
• Application #: 2094954
• Study Section: Special Emphasis Panel (ZRG4-PTHA (01))
• Project Start: 1990-09-01
• Project End: 2000-05-31
• Budget Start: 1996-06-01
• Budget End: 1997-05-31
• Support Year: 7
• Fiscal Year: 1996

Institution

• Name: Northwestern University at Chicago
• Department: Microbiology/Immun/Virology
• Type: Schools of Dentistry
• DUNS #: 005436803
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60611

Publications

Volpert, Olga V; Zaichuk, Tetiana; Zhou, Wei et al. (2002) Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 8:349-57

Lingen, M W; DiPietro, L A; Solt, D B et al. (1997) The angiogenic switch in hamster buccal pouch keratinocytes is dependent on TGFbeta-1 and is unaffected by ras activation. Carcinogenesis 18:329-38

Tolsma, S S; Stack, M S; Bouck, N (1997) Lumen formation and other angiogenic activities of cultured capillary endothelial cells are inhibited by thrombospondin-1. Microvasc Res 54:13-26

Lingen, M W; Polverini, P J; Bouck, N P (1996) Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic. Am J Pathol 149:247-58

Lingen, M W; Polverini, P J; Bouck, N P (1996) Inhibition of squamous cell carcinoma angiogenesis by direct interaction of retinoic acid with endothelial cells. Lab Invest 74:476-83