Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA054192-03
Application #
2095731
Study Section
Virology Study Section (VR)
Project Start
1994-05-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Missouri-Columbia
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
112205955
City
Columbia
State
MO
Country
United States
Zip Code
65211
Swamynathan, Shivalingappa K; Varma, Balwantkumar R; Weber, Karl T et al. (2002) Targeted disruption of one allele of the Y-box protein gene, Chk-YB-1b, in DT40 cells results in major defects in cell cycle. Biochem Biophys Res Commun 296:451-7
Swamynathan, S K; Nambiar, A; Guntaka, R V (2000) Chicken Y-box proteins chk-YB-1b and chk-YB-2 repress translation by sequence-specific interaction with single-stranded RNA. Biochem J 348 Pt 2:297-305
Swamynathan, S K; Nambiar, A; Guntaka, R V (1998) Role of single-stranded DNA regions and Y-box proteins in transcriptional regulation of viral and cellular genes. FASEB J 12:515-22
Nambiar, A; Swamynathan, S K; Kandala, J C et al. (1998) Characterization of the DNA-binding domain of the avian Y-box protein, chkYB-2, and mutational analysis of its single-strand binding motif in the Rous sarcoma virus enhancer. J Virol 72:900-9
Nambiar, A; Kandala, J C; Svoboda, J et al. (1998) Cloning of a novel Y-box homology protein (chkYB-1HP) cDNA lacking the cold-shock domain. Biochim Biophys Acta 1395:1-6
Dhalla, A K; Ririe, S S; Swamynathan, S K et al. (1998) chk-YB-1b, a Y-box binding protein activates transcription from rat alpha1(I) procollagen gene promoter. Biochem J 336 ( Pt 2):373-9
Guntaka, R V; Swamynathan, S K (1998) Retroviral vectors for gene therapy. Indian J Exp Biol 36:539-45
Swamynathan, S K; Nambiar, A; Guntaka, R V (1997) Chicken YB-2, a Y-box protein, is a potent activator of Rous sarcoma virus long terminal repeat-driven transcription in avian fibroblasts. J Virol 71:2873-80
Cleavinger, P J; Kandala, J C; Guntaka, R V (1997) The GT-rich sequence in the U5 region of Rous sarcoma virus long terminal repeat is required for transcription termination and 3' processing. Folia Biol (Praha) 43:153-60
Cleavinger, P J; Shin, B A; Kandala, J C et al. (1996) Cloning of Rous sarcoma virus enhancer factor genes. II. RSV-EF-II, abundantly expressed in fibroblasts and muscle tissue, binds to an octamer sequence, 5'-GTACCACC-3', in the noncoding strand of RSV enhancer. Virology 222:133-43

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