Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA055893-03
Application #
2096987
Study Section
Radiation Study Section (RAD)
Project Start
1993-05-01
Project End
1997-04-30
Budget Start
1995-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Engelhardt, Edward L; Schneider, Richard F; Seeholzer, Steven H et al. (2002) The synthesis and radiolabeling of 2-nitroimidazole derivatives of cyclam and their preclinical evaluation as positive markers of tumor hypoxia. J Nucl Med 43:837-50
Iyer, R V; Haynes, P T; Schneider, R F et al. (2001) Marking hypoxia in rat prostate carcinomas with beta-D-[125I]azomycin galactopyranoside and. J Nucl Med 42:337-44
Chapman, J D; Schneider, R F; Urbain, J L et al. (2001) Single-photon emission computed tomography and positron-emission tomography assays for tissue oxygenation. Semin Radiat Oncol 11:47-57
Iyer, R V; Kim, E; Schneider, R F et al. (1998) A dual hypoxic marker technique for measuring oxygenation change within individual tumors. Br J Cancer 78:163-9
Iyer, R V; Engelhardt, E L; Stobbe, C C et al. (1998) Preclinical assessment of hypoxic marker specificity and sensitivity. Int J Radiat Oncol Biol Phys 42:741-5
Chapman, J D; Engelhardt, E L; Stobbe, C C et al. (1998) Measuring hypoxia and predicting tumor radioresistance with nuclear medicine assays. Radiother Oncol 46:229-37
Chapman, J D; Coia, L R; Stobbe, C C et al. (1996) Prediction of tumour hypoxia and radioresistance with nuclear medicine markers. Br J Cancer Suppl 27:S204-8
Yeh, K A; Biade, S; Lanciano, R M et al. (1995) Polarographic needle electrode measurements of oxygen in rat prostate carcinomas: accuracy and reproducibility. Int J Radiat Oncol Biol Phys 33:111-8
Joseph, P; Jaiswal, A K; Stobbe, C C et al. (1994) The role of specific reductases in the intracellular activation and binding of 2-nitroimidazoles. Int J Radiat Oncol Biol Phys 29:351-5