Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA056115-02
Application #
3200614
Study Section
Special Emphasis Panel (SRC)
Project Start
1991-05-01
Project End
1994-04-30
Budget Start
1992-05-01
Budget End
1993-04-30
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Duke University
Department
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Sampson, J H; Ashley, D M; Archer, G E et al. (1997) Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion. Neurosurgery 41:1365-72; discussion 1372-3
Hare, C B; Elion, G B; Houghton, P J et al. (1997) Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against pediatric and adult central nervous system tumor xenografts. Cancer Chemother Pharmacol 39:187-91
Sampson, J H; Archer, G E; Ashley, D M et al. (1996) Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the ""immunologically privileged"" central nervous system. Proc Natl Acad Sci U S A 93:10399-404
Moynihan, K; Elion, G B; Ali-Osman, F et al. (1996) Enhancement of melphalan activity by inhibition of DNA polymerase-alpha and DNA polymerase-beta. Cancer Chemother Pharmacol 38:349-54
McLendon, R E; Fung, K M; Bentley, R C et al. (1996) Production and characterization of two ependymoma xenografts. J Neuropathol Exp Neurol 55:540-8
Dong, Q; Bullock, N; Ali-Osman, F et al. (1996) Repair analysis of 4-hydroperoxycyclophosphamide-induced DNA interstrand crosslinking in the c-myc gene in 4-hydroperoxycyclophosphamide-sensitive and -resistant medulloblastoma cell lines. Cancer Chemother Pharmacol 37:242-46
Kurpad, S N; Friedman, H S; Archer, G E et al. (1995) Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats. Cancer Res 55:3803-9
Foltz, R M; McLendon, R E; Friedman, H S et al. (1995) A pial window model for the intracranial study of human glioma microvascular function. Neurosurgery 36:976-84;discussion 984-5
Batra, S K; Castelino-Prabhu, S; Wikstrand, C J et al. (1995) Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene. Cell Growth Differ 6:1251-9
Kurpad, S N; Zhao, X G; Wikstrand, C J et al. (1995) Tumor antigens in astrocytic gliomas. Glia 15:244-56

Showing the most recent 10 out of 33 publications