Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA056736-05
Application #
2097547
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1992-04-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1998-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Genetics
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Roninson, Igor B; Gudkov, Andrei V (2003) Genetic suppressor elements in the characterization and identification of tumor suppressor genes. Methods Mol Biol 222:413-36
Levenson, V V; Lausch, E; Kirschling, D J et al. (1999) A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication. Somat Cell Mol Genet 25:9-26
Dunn, S J; Park, S W; Sharma, V et al. (1999) Isolation of efficient antivirals: genetic suppressor elements against HIV-1. Gene Ther 6:130-7
Axenovich, S A; Kazarov, A R; Boiko, A D et al. (1998) Altered expression of ubiquitous kinesin heavy chain results in resistance to etoposide and hypersensitivity to colchicine: mapping of the domain associated with drug response. Cancer Res 58:3423-8
Roninson, I B; Zuhn, D; Ruth, A et al. (1998) Isolation of altered-function mutants and genetic suppressor elements of multidrug transporter P-glycoprotein by expression selection from retroviral libraries. Methods Enzymol 292:225-48
Gudkov, A V; Roninson, I B (1997) Isolation of genetic suppressor elements (GSEs) from random fragment cDNA libraries in retroviral vectors. Methods Mol Biol 69:221-40
Schott, B; Kandel, E S; Roninson, I B (1997) Efficient recovery and regeneration of integrated retroviruses. Nucleic Acids Res 25:2940-2
Gallagher, W M; Cairney, M; Schott, B et al. (1997) Identification of p53 genetic suppressor elements which confer resistance to cisplatin. Oncogene 14:185-93
Kandel, E S; Chang, B D; Schott, B et al. (1997) Applications of green fluorescent protein as a marker of retroviral vectors. Somat Cell Mol Genet 23:325-40
Chang, B D; Roninson, I B (1996) Inducible retroviral vectors regulated by lac repressor in mammalian cells. Gene 183:137-42

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