Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA056796-04
Application #
2097597
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1993-01-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Michigan State University
Department
Internal Medicine/Medicine
Type
Schools of Osteopathy
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824

  Publications

Lawrence, C W; Maher, V M (2001) Eukaryotic mutagenesis and translesion replication dependent on DNA polymerase zeta and Rev1 protein. Biochem Soc Trans 29:187-91
Lawrence, C W; Maher, V M (2001) Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p. Philos Trans R Soc Lond B Biol Sci 356:41-6
Gibbs, P E; Wang, X D; Li, Z et al. (2000) The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light. Proc Natl Acad Sci U S A 97:4186-91
Lawrence, C W; Gibbs, P E; Murante, R S et al. (2000) Roles of DNA polymerase zeta and Rev1 protein in eukaryotic mutagenesis and translesion replication. Cold Spring Harb Symp Quant Biol 65:61-9
McGregor, W G; Wei, D; Maher, V M et al. (1999) Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light. Mol Cell Biol 19:147-54
Gibbs, P E; McGregor, W G; Maher, V M et al. (1998) A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Proc Natl Acad Sci U S A 95:6876-80
McGregor, W G; Wei, D; Chen, R H et al. (1997) Relationship between adduct formation, rates of excision repair and the cytotoxic and mutagenic effects of structurally-related polycyclic aromatic carcinogens. Mutat Res 376:143-52
Tung, B S; McGregor, W G; Wang, Y C et al. (1996) Comparison of the rate of excision of major UV photoproducts in the strands of the human HPRT gene of normal and xeroderma pigmentosum variant cells. Mutat Res 362:65-74
Wei, D; Maher, V M; McCormick, J J (1996) Site-specific excision repair of 1-nitrosopyrene-induced DNA adducts at the nucleotide level in the HPRT gene of human fibroblasts: effect of adduct conformation on the pattern of site-specific repair. Mol Cell Biol 16:3714-9
Wei, D; Maher, V M; McCormick, J J (1996) Effect of nuclear environment on the distribution of benzo[a]pyrene diol epoxide-induced adducts in the HPRT gene of human fibroblasts. Carcinogenesis 17:2695-701

Showing the most recent 10 out of 13 publications