Egf Signal Transduction and Radiation Response

Laderoute, Keith R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 3R01CA057333-03S1
• Application #: 2098067
• Study Section: Radiation Study Section (RAD)
• Project Start: 1994-03-01
• Project End: 1998-02-28
• Budget Start: 1996-03-01
• Budget End: 1998-02-28
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Sri International
• City: Menlo Park
• State: CA
• Country: United States
• Zip Code: 94025

Publications

Laderoute, K R; Webster, K A (1997) Hypoxia/reoxygenation stimulates Jun kinase activity through redox signaling in cardiac myocytes. Circ Res 80:336-44

Mazure, N M; Chen, E Y; Laderoute, K R et al. (1997) Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 90:3322-31

Mazure, N M; Chen, E Y; Yeh, P et al. (1996) Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression. Cancer Res 56:3436-40

Laderoute, K R; Knapp, A M; Green, C J et al. (1996) Expression of the ATDC (ataxia telangiectasia group D-complementing) gene in A431 human squamous carcinoma cells. Int J Cancer 66:772-8