Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA057496-05
Application #
2098235
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1992-09-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
009214214
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Jiang, G l; Liu, L; Buyse, I M et al. (1999) Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1. Int J Cancer 83:541-6
Huang, S; Shao, G; Liu, L (1998) The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. J Biol Chem 273:15933-9
He, L; Yu, J X; Liu, L et al. (1998) RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis. Cancer Res 58:4238-44
Buyse, I M; Huang, S (1997) In vitro analysis of the E1A-homologous sequences of RIZ. J Virol 71:6200-3
Liu, L; Shao, G; Steele-Perkins, G et al. (1997) The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter. J Biol Chem 272:2984-91
Xie, M; Shao, G; Buyse, I M et al. (1997) Transcriptional repression mediated by the PR domain zinc finger gene RIZ. J Biol Chem 272:26360-6
Mock, B A; Liu, L; LePaslier, D et al. (1996) The B-lymphocyte maturation promoting transcription factor BLIMP1/PRDI-BF1 maps to D6S447 on human chromosome 6q21-q22.1 and the syntenic region of mouse chromosome 10. Genomics 37:24-8
Mock, B A; Coleman, M P; Huang, S (1996) Riz maps to distal chromosome 4 near genes involved in tumorigenesis and nerve degeneration. Mamm Genome 7:637
Buyse, I M; Takahashi, E I; Huang, S (1996) Physical mapping of the retinoblastoma interacting zinc finger gene RIZ to D1S228 on chromosome 1p36. Genomics 34:119-21