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Dahl, E L; Mulcahy, R T (2001) Cell-type specific differences in glutamate cysteine ligase transcriptional regulation demonstrate independent subunit control. Toxicol Sci 61:265-72
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Wild, A C; Mulcahy, R T (2000) Regulation of gamma-glutamylcysteine synthetase subunit gene expression: insights into transcriptional control of antioxidant defenses. Free Radic Res 32:281-301
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Gipp, J J; Mulcahy, R T (2000) Structure of the human glutamate-L-cysteine ligase catalytic (GLCLC) subunit gene. Cytogenet Cell Genet 88:130-2
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Zipper, L M; Mulcahy, R T (2000) Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes. Biochem Biophys Res Commun 278:484-92
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Wild, A C; Moinova, H R; Mulcahy, R T (1999) Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. J Biol Chem 274:33627-36
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Moinova, H R; Mulcahy, R T (1999) Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element. Biochem Biophys Res Commun 261:661-8
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Griffith, O W; Mulcahy, R T (1999) The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase. Adv Enzymol Relat Areas Mol Biol 73:209-67, xii
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Moellering, D; Mc Andrew, J; Patel, R P et al. (1999) The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase. FEBS Lett 448:292-6
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Wild, A C; Mulcahy, R T (1999) Pyrrolidine dithiocarbamate up-regulates the expression of the genes encoding the catalytic and regulatory subunits of gamma-glutamylcysteine synthetase and increases intracellular glutathione levels. Biochem J 338 ( Pt 3):659-65
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Wild, A C; Gipp, J J; Mulcahy, T (1998) Overlapping antioxidant response element and PMA response element sequences mediate basal and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase catalytic subunit gene. Biochem J 332 ( Pt 2):373-81
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