Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA057970-04
Application #
2098673
Study Section
Special Emphasis Panel (SRC (66))
Project Start
1992-07-15
Project End
1997-04-30
Budget Start
1995-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Yale University
Department
Veterinary Sciences
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Sundaram, P; Tigelaar, R E; Xiao, W et al. (1998) Intracutaneous vaccination of rabbits with the E6 gene of cottontail rabbit papillomavirus provides partial protection against virus challenge. Vaccine 16:613-23
Sundaram, P; Tigelaar, R E; Brandsma, J L (1997) Intracutaneous vaccination of rabbits with the cottontail rabbit papillomavirus (CRPV) L1 gene protects against virus challenge . Vaccine 15:664-71
Xiao, W; Brandsma, J L (1996) High efficiency, long-term clinical expression of cottontail rabbit papillomavirus (CRPV) DNA in rabbit skin following particle-mediated DNA transfer. Nucleic Acids Res 24:2620-2
Sundaram, P; Brandsma, J L (1996) Rapid, efficient, large-scale purification of unfused, non-denatured E7 protein of cottontail rabbit papillomavirus. J Virol Methods 57:61-70
Sundaram, P; Xiao, W; Brandsma, J L (1996) Particle-mediated delivery of recombinant expression vectors to rabbit skin induces high-titered polyclonal antisera (and circumvents purification of a protein immunogen). Nucleic Acids Res 24:1375-7
Sundaram, P (1996) A simplified 'coupled' probing approach for the detection of proteins on dot and western blots. J Immunol Methods 195:149-52
Brandsma, J L; Brownstein, D G; Xiao, W et al. (1995) Papilloma formation in human foreskin xenografts after inoculation of human papillomavirus type 16 DNA. J Virol 69:2716-21
Wu, X; Xiao, W; Brandsma, J L (1994) Papilloma formation by cottontail rabbit papillomavirus requires E1 and E2 regulatory genes in addition to E6 and E7 transforming genes. J Virol 68:6097-102