Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA058642-03
Application #
2099322
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1994-09-01
Project End
1996-10-31
Budget Start
1996-09-01
Budget End
1996-10-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Chai, Y; Chipitsyna, G; Cui, J et al. (2001) c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells. Oncogene 20:1357-67
Fujimura, Y; Siddique, H; Lee, L et al. (2001) EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function. Oncogene 20:6653-9
Chai, Y L; Cui, J; Shao, N et al. (1999) The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter. Oncogene 18:263-8
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Shao, N; Chai, Y; Cui, J Q et al. (1998) Induction of apoptosis by Elk-1 and deltaElk-1 proteins. Oncogene 17:527-32
Cui, J Q; Shao, N; Chai, Y et al. (1998) BRCA1 splice variants BRCA1a and BRCA1b associate with CBP co-activator. Oncol Rep 5:591-5
Dhulipala, P D; Lee, L; Rao, V N et al. (1998) Fli-1b is generated by usage of differential splicing and alternative promoter. Oncogene 17:1149-57
Siddique, H; Zou, J P; Rao, V N et al. (1998) The BRCA2 is a histone acetyltransferase. Oncogene 16:2283-5
Yi, H; Fujimura, Y; Ouchida, M et al. (1997) Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias. Oncogene 14:1259-68
Shao, N; Chai, Y L; Shyam, E et al. (1996) Induction of apoptosis by the tumor suppressor protein BRCA1. Oncogene 13:1-7

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