Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA058704-04
Application #
2099393
Study Section
Pathology B Study Section (PTHB)
Project Start
1993-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Southern California
Department
Pathology
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Blake, C; Tsao, J L; Wu, A et al. (2001) Stepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancers. Am J Pathol 158:1867-70
Ireland, A P; Shibata, D K; Chandrasoma, P et al. (2000) Clinical significance of p53 mutations in adenocarcinoma of the esophagus and cardia. Ann Surg 231:179-87
Tsao, J L; Yatabe, Y; Salovaara, R et al. (2000) Genetic reconstruction of individual colorectal tumor histories. Proc Natl Acad Sci U S A 97:1236-41
Tsao, J L; Yatabe, Y; Markl, I D et al. (2000) Bladder cancer genotype stability during clinical progression. Genes Chromosomes Cancer 29:26-32
Tsao, J L; Tavare, S; Salovaara, R et al. (1999) Colorectal adenoma and cancer divergence. Evidence of multilineage progression. Am J Pathol 154:1815-24
Baker, S M; Harris, A C; Tsao, J L et al. (1998) Enhanced intestinal adenomatous polyp formation in Pms2-/-;Min mice. Cancer Res 58:1087-9
Tsao, J L; Zhang, J; Salovaara, R et al. (1998) Tracing cell fates in human colorectal tumors from somatic microsatellite mutations: evidence of adenomas with stem cell architecture. Am J Pathol 153:1189-200
Shibata, D (1998) The dynamics of early intestinal tumour proliferation: to be or not to be. Cancer Surv 32:181-200
Shibata, D (1997) Molecular tumor clocks and dynamic phenotype. Am J Pathol 151:643-6
Tsao, J L; Davis, S D; Baker, S M et al. (1997) Intestinal stem cell division and genetic diversity. A computer and experimental analysis. Am J Pathol 151:573-9

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