Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA059832-03
Application #
2100455
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1993-05-15
Project End
1997-04-30
Budget Start
1995-06-05
Budget End
1997-04-30
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Reed, C; Fu, Z Q; Wu, J et al. (1997) Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2. Protein Eng 10:1101-7
Fu, Z Q; Harrison, R W; Reed, C et al. (1995) Model complexes of tumor necrosis factor-alpha with receptors R1 and R2. Protein Eng 8:1233-41
Chen, P C; DuBois, G C; Chen, M J (1995) Mapping the domain(s) critical for the binding of human tumor necrosis factor-alpha to its two receptors. J Biol Chem 270:2874-8